MolNFT v1 · #461156 · protein
AlphaFold monomer V2.0 prediction for telomerase reverse transcriptase (O00939)
O00939: “AlphaFold monomer V2.0 prediction for telomerase reverse transcriptase (O00939)”. 13 pockets (best druggability 0.69). MolNFT v1 #461156 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O00939
- Type
- protein
- Length
- 1,031 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xa73BAb1DabE4333A884D03393eAa10c3B4215494
- Molecule
- Telomerase reverse transcriptase
- UniProt
- O00939
- Pockets
- 13 · best druggability 0.69
Structure
1 distinct chain · 51% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Telomerase reverse transcriptase | protein | 1031 | 51% helix, 14% strand | O00939 |
Pockets
13 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 837 | 0.69 | 0.76 | 62 | empty |
| 2 | 538 | 0.66 | 0.77 | 49 | empty |
| 3 | 181 | 0.62 | 0.84 | 18 | empty |
| 4 | 357 | 0.59 | 0.77 | 44 | empty |
| 5 | 340 | 0.56 | 0.75 | 46 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O00939
- Elsewhere: UniProt O00939 · AlphaFold DB O00939
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