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AlphaFold monomer V2.0 prediction for telomerase reverse transcriptase (O00939)

Analyse AlphaFold monomer V2.0 prediction for telomerase reverse transcriptase (O00939) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: O00939
Type: protein
Length: 1,031 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xa73BAb1DabE4333A884D03393eAa10c3B4215494
Molecule: Telomerase reverse transcriptase
UniProt: O00939
Pockets: 13 · best druggability 0.69

Structure

1 distinct chain · 51% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Telomerase reverse transcriptase	protein	1031	51% helix, 14% strand	O00939

Pockets

13 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	837	0.69	0.76	62	empty
2	538	0.66	0.77	49	empty
3	181	0.62	0.84	18	empty
4	357	0.59	0.77	44	empty
5	340	0.56	0.75	46	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O00939
Elsewhere: UniProt O00939 · AlphaFold DB O00939

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