MolNFT v1 · #459776 · protein
AlphaFold monomer V2.0 prediction for telomerase cajal body protein 1 (Q9BUR4)
Q9BUR4: “AlphaFold monomer V2.0 prediction for telomerase cajal body protein 1 (Q9BUR4)”. 4 pockets (best druggability 0.77). MolNFT v1 #459776 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9BUR4
- Type
- protein
- Length
- 548 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x46EfCa788d03A3e879DAcDb96552AB8Bbc7e20b3
- Molecule
- Telomerase cajal body protein 1
- UniProt
- Q9BUR4
- Pockets
- 4 · best druggability 0.77
Structure
1 distinct chain · 3% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Telomerase cajal body protein 1 | protein | 548 | 3% helix, 30% strand | Q9BUR4 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 604 | 0.77 | 0.83 | 41 | empty |
| 2 | 363 | 0.63 | 0.79 | 37 | empty |
| 3 | 83 | 0.35 | 0.75 | 18 | empty |
| 4 | 69 | 0.28 | 0.73 | 15 | empty |
Compared structures
- 7V9A · Biogenesis module of human telomerase holoenzyme · an experimental structure of the same protein · chain A against B, TM-score 0.64
- 7TRC · Human telomerase H/ACA rnp at 3.3 ångström · an experimental structure of the same protein · chain A against K, TM-score 0.59
- 7BGB · The H/ACA rnp lobe of human telomerase · an experimental structure of the same protein · chain A against K, TM-score 0.56
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BUR4
- Elsewhere: UniProt Q9BUR4 · AlphaFold DB Q9BUR4
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