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AlphaFold monomer V2.0 prediction for telomerase cajal body protein 1 (Q9BUR4)

Analyse AlphaFold monomer V2.0 prediction for telomerase cajal body protein 1 (Q9BUR4) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9BUR4
Type
protein
Length
548 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x46EfCa788d03A3e879DAcDb96552AB8Bbc7e20b3
Molecule
Telomerase cajal body protein 1
UniProt
Q9BUR4
Pockets
4 · best druggability 0.77

Structure

1 distinct chain · 3% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATelomerase cajal body protein 1protein5483% helix, 30% strandQ9BUR4

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16040.770.8341empty
23630.630.7937empty
3830.350.7518empty
4690.280.7315empty

Compared structures

  • 7V9A · Biogenesis module of human telomerase holoenzyme · an experimental structure of the same protein · chain A against B, TM-score 0.64
  • 7V9A · biogenesis module of human telomerase holoenzyme · an experimental structure of the same protein · chain A against B, TM-score 0.64
  • 8OUE · The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in a semi-closed… · an experimental structure of the same protein · chain A against K, TM-score 0.63
  • 8OUF · The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in an open… · an experimental structure of the same protein · chain A against K, TM-score 0.63
  • 7TRC · Human telomerase H/ACA rnp at 3.3 ångström · an experimental structure of the same protein · chain A against K, TM-score 0.59
  • 7TRC · Human telomerase H/ACA RNP at 3.3 Angstrom · an experimental structure of the same protein · chain A against K, TM-score 0.59
  • 7BGB · The H/ACA RNP lobe of human telomerase · an experimental structure of the same protein · chain A against K, TM-score 0.56
  • 7BGB · The H/ACA rnp lobe of human telomerase · an experimental structure of the same protein · chain A against K, TM-score 0.56

Analyse

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