MolNFT v1 · #457898 · protein
AlphaFold monomer V2.0 prediction for antigen peptide transporter 2 (Q03519)
Q03519: “AlphaFold monomer V2.0 prediction for antigen peptide transporter 2 (Q03519)”. 7 pockets (best druggability 0.64). MolNFT v1 #457898 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q03519
- Type
- protein
- Length
- 686 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x46EfCa788d03A3e879DAcDb96552AB8Bbc7e20b3
- Molecule
- Antigen peptide transporter 2
- UniProt
- Q03519
- Pockets
- 7 · best druggability 0.64
Structure
1 distinct chain · 69% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Antigen peptide transporter 2 | protein | 686 | 69% helix, 8% strand | Q03519 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 86 | 0.64 | 0.90 | 16 | empty |
| 2 | 438 | 0.60 | 0.75 | 46 | empty |
| 3 | 172 | 0.57 | 0.81 | 31 | empty |
| 4 | 127 | 0.46 | 0.78 | 23 | empty |
| 5 | 201 | 0.46 | 0.74 | 26 | empty |
Compared structures
- 8T4E · Transporter associated with antigen processing (TAP) bound to the 9-mer peptide ILKEPVHGV · an experimental structure of the same protein · chain A against B, TM-score 0.78
- 8T4G · Transporter associated with antigen processing (TAP) bound to the 9-mer peptide QYDDAVYKL · an experimental structure of the same protein · chain A against B, TM-score 0.78
- 8T4H · Transporter associated with antigen processing (TAP) bound to the 8-mer peptide RRYQSTEL · an experimental structure of the same protein · chain A against B, TM-score 0.77
- 8T4I · Transporter associated with antigen processing (TAP) bound to the 7-mer peptide RRYSTEL · an experimental structure of the same protein · chain A against B, TM-score 0.76
- 8T4F · Transporter associated with antigen processing (TAP) bound to the 9-mer peptide RRYQKSTEL · an experimental structure of the same protein · chain A against B, TM-score 0.76
- 8T4J · Transporter associated with antigen processing (TAP) bound to the 14-mer peptide… · an experimental structure of the same protein · chain A against B, TM-score 0.75
- 5U1D · Cryo-EM structure of the human TAP ATP-Binding Cassette Transporter · an experimental structure of the same protein · chain A against B, TM-score 0.69
- 5U1D · Cryo-EM structure of the human tap ATP-binding cassette transporter · an experimental structure of the same protein · chain A against B, TM-score 0.69
- 8T46 · Transporter associated with antigen processing (TAP) in the apo state · an experimental structure of the same protein · chain A against B, TM-score 0.68
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q03519
- Elsewhere: UniProt Q03519 · AlphaFold DB Q03519
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