MolNFT v1 · #457011 · protein
AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 1-like (Q8IZX4)
Q8IZX4: “AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 1-like (Q8IZX4)”. 20 pockets (best druggability 0.69). MolNFT v1 #457011 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8IZX4
- Type
- protein
- Length
- 1,826 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB35df660264f41795De49C83276C108A4ba91ADE
- Molecule
- Transcription initiation factor tfiid subunit 1-like
- UniProt
- Q8IZX4
- Pockets
- 20 · best druggability 0.69
Structure
1 distinct chain · 31% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcription initiation factor tfiid subunit 1-like | protein | 1826 | 31% helix, 5% strand | Q8IZX4 |
Pockets
20 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 479 | 0.69 | 0.79 | 45 | empty |
| 2 | 664 | 0.64 | 0.74 | 45 | empty |
| 3 | 597 | 0.62 | 0.74 | 52 | empty |
| 4 | 340 | 0.62 | 0.79 | 32 | empty |
| 5 | 444 | 0.61 | 0.76 | 48 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 3HMH · Crystal structure of the second bromodomain of human TBP-associated factor RNA polymerase… · an experimental structure of the same protein · chain A against A, TM-score 0.07
- 3HMH · Crystal structure of the second bromodomain of human tbp-associated factor RNA polymerase… · an experimental structure of the same protein · chain A against A, TM-score 0.07
- 5IGL · Crystal structure of the second bromodomain of human TAF1L in complex with bromosporine… · an experimental structure of the same protein · chain A against A, TM-score 0.06
- 5IGL · Crystal structure of the second bromodomain of human TAF1L in complex with bromosporine… · an experimental structure of the same protein · chain A against A, TM-score 0.06
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IZX4
- Elsewhere: UniProt Q8IZX4 · AlphaFold DB Q8IZX4
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