MolNFT v1 · #444354 · protein
AlphaFold monomer V2.0 prediction for aspartate--tRNA ligase, cytoplasmic (P14868)
P14868: “AlphaFold monomer V2.0 prediction for aspartate--tRNA ligase, cytoplasmic (P14868)”. 7 pockets (best druggability 0.72). MolNFT v1 #444354 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P14868
- Type
- protein
- Length
- 501 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
- Molecule
- Aspartate--tRNA ligase, cytoplasmic
- UniProt
- P14868
- Pockets
- 7 · best druggability 0.72
Structure
1 distinct chain · 30% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Aspartate--tRNA ligase, cytoplasmic | protein | 501 | 30% helix, 26% strand | P14868 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 460 | 0.72 | 0.82 | 51 | empty |
| 2 | 65 | 0.53 | 0.87 | 22 | empty |
| 3 | 216 | 0.51 | 0.76 | 26 | empty |
| 4 | 54 | 0.44 | 0.84 | 15 | empty |
| 5 | 57 | 0.36 | 0.79 | 15 | empty |
Compared structures
- 4J15 · Crystal structure of human cytosolic aspartyl-tRNA synthetase, a component of multi-tRNA… · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 4J15 · Crystal structure of human cytosolic aspartyl-tRNA synthetase, a component of multi-tRNA… · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 6IY6 · Crystal structure of human cytosolic aspartyl-tRNA synthetase (drs) in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.83
- 6IY6 · Crystal structure of human cytosolic aspartyl-tRNA synthetase (DRS) in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.83
- 5Y6L · A subcomplex crystal structure of human cytosolic aspartyl-tRNA synthetase and… · an experimental structure of the same protein · chain A against E, TM-score 0.12
- 5Y6L · A subcomplex crystal structure of human cytosolic aspartyl-tRNA synthetase and… · an experimental structure of the same protein · chain A against E, TM-score 0.12
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14868
- Elsewhere: UniProt P14868 · AlphaFold DB P14868
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.