MolNFT v1 · #443622 · protein
AlphaFold monomer V2.0 prediction for syncytin-1 (Q9UQF0)
Q9UQF0: “AlphaFold monomer V2.0 prediction for syncytin-1 (Q9UQF0)”. 6 pockets (best druggability 0.77). MolNFT v1 #443622 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9UQF0
- Type
- protein
- Length
- 538 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3298b100681D3A2372Bba3b2f282750dD71629B9
- Molecule
- Syncytin-1
- UniProt
- Q9UQF0
- Pockets
- 6 · best druggability 0.77
Structure
1 distinct chain · 36% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Syncytin-1 | protein | 538 | 36% helix, 15% strand | Q9UQF0 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 833 | 0.77 | 0.80 | 66 | empty |
| 2 | 301 | 0.57 | 0.77 | 32 | empty |
| 3 | 225 | 0.49 | 0.74 | 34 | empty |
| 4 | 95 | 0.37 | 0.75 | 23 | empty |
| 5 | 63 | 0.34 | 0.76 | 12 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Compared structures
- 8OUH · Complex of human ASCT2 with Syncytin-1 · an experimental structure of the same protein · chain A against D, TM-score 0.20
- 8OUJ · Heterotrimeric Complex of Human ASCT2 with Syncytin-1 · an experimental structure of the same protein · chain A against D, TM-score 0.20
- 5HA6 · Crystal structure of human syncytin-1 fusion subunit · an experimental structure of the same protein · chain A against B, TM-score 0.08
- 5HA6 · Crystal structure of human syncytin-1 fusion subunit · an experimental structure of the same protein · chain A against B, TM-score 0.08
- 6RX1 · Crystal structure of human syncytin 1 in post-fusion conformation · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 6RX1 · Crystal structure of human syncytin 1 in post-fusion conformation · an experimental structure of the same protein · chain A against A, TM-score 0.08
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UQF0
- Elsewhere: UniProt Q9UQF0 · AlphaFold DB Q9UQF0
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