MolNFT v1 · #443201 · protein

AlphaFold monomer V2.0 prediction for alanine--tRNA ligase (O27718)

O27718: “AlphaFold monomer V2.0 prediction for alanine--tRNA ligase (O27718)”. 9 pockets (best druggability 0.69). MolNFT v1 #443201 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O27718
Type: protein
Length: 898 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x5BeA89782341f98147F2D811B063F91F0aE7D7bF
Molecule: Alanine--tRNA ligase
UniProt: O27718
Pockets: 9 · best druggability 0.69

Structure

1 distinct chain · 44% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alanine--tRNA ligase	protein	898	44% helix, 23% strand	O27718

Pockets

9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	460	0.69	0.80	55	empty
2	386	0.62	0.77	44	empty
3	199	0.59	0.81	31	empty
4	271	0.57	0.78	29	empty
5	155	0.48	0.77	30	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O27718
Elsewhere: UniProt O27718 · AlphaFold DB O27718

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