MolNFT v1 · #439163 · protein
AlphaFold monomer V2.0 prediction for SH3 and cysteine-rich domain- containing protein 3 (Q96MF2)
Q96MF2 · SH3 and cysteine-rich domain-containing protein 3: “AlphaFold monomer V2.0 prediction for SH3 and cysteine-rich domain- containing protein 3 (Q96MF2)”. 4 pockets (best druggability 0.69). MolNFT v1 #439163 on GenesisL1: 3D…
- Accession
- Q96MF2
- Type
- protein
- Length
- 364 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x013d37A39613599f6f82870f7F3B3DDe53b34038
- Molecule
- SH3 and cysteine-rich domain-containing protein 3
- UniProt
- Q96MF2
- Pockets
- 4 · best druggability 0.69
Structure
1 distinct chain · 15% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SH3 and cysteine-rich domain-containing protein 3 | protein | 364 | 15% helix, 20% strand | Q96MF2 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 570 | 0.69 | 0.78 | 61 | empty |
| 2 | 158 | 0.45 | 0.75 | 26 | empty |
| 3 | 105 | 0.38 | 0.75 | 21 | empty |
| 4 | 115 | 0.38 | 0.74 | 17 | empty |
Compared structures
- 6UY9 · Crystal structure of the STAC3 tandem SH3 domains - P269R, W284S · an experimental structure of the same protein · chain A against A, TM-score 0.33
- 6UY9 · Crystal structure of the STAC3 tandem SH3 domains - P269R, W284S · an experimental structure of the same protein · chain A against A, TM-score 0.33
- 6UY8 · Crystal structure of the STAC3 tandem SH3 domains - P269R, K329N · an experimental structure of the same protein · chain A against A, TM-score 0.32
- 6UY8 · Crystal structure of the STAC3 tandem SH3 domains - P269R, K329N · an experimental structure of the same protein · chain A against A, TM-score 0.32
- 6UY7 · Crystal structure of the STAC3 tandem SH3 domains - P269R · an experimental structure of the same protein · chain A against A, TM-score 0.30
- 6UY7 · Crystal structure of the STAC3 tandem SH3 domains - P269R · an experimental structure of the same protein · chain A against A, TM-score 0.30
- 2DB6 · Solution structure of rsgi ruh-051, a C1 domain of STAC3 from human cdna · an experimental structure of the same protein · chain A against A, TM-score 0.17
- 2DB6 · Solution structure of RSGI RUH-051, a C1 domain of STAC3 from human cDNA · an experimental structure of the same protein · chain A against A, TM-score 0.17
- 6B29 · Crystal structure of the second SH3 domain of STAC3 (309-364) · an experimental structure of the same protein · chain A against B, TM-score 0.16
- 6B29 · Crystal structure of the second SH3 domain of STAC3 (309-364) · an experimental structure of the same protein · chain A against B, TM-score 0.16
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96MF2
- Elsewhere: UniProt Q96MF2 · AlphaFold DB Q96MF2
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