UniProt Q96MF2
SH3 and cysteine-rich domain-containing protein 3 (Q96MF2)
SH3 and cysteine-rich domain-containing protein 3 (UniProt Q96MF2): 9 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q96MF2
- Protein
- SH3 and cysteine-rich domain-containing protein 3
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 4 · 1 record with a druggable one
Structures
10 records of Q96MF2 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DB6 | Solution structure of RSGI RUH-051, a C1 domain of STAC3 from human cDNA | solution nmr | A | — | — |
| 2DB6 | Solution structure of rsgi ruh-051, a C1 domain of STAC3 from human cdna | solution nmr | A | — | — |
| 6B29 | Crystal structure of the second SH3 domain of STAC3 (309-364) | x-ray diffraction | A, B, C, D | — | — |
| 6UY7 | Crystal structure of the STAC3 tandem SH3 domains - P269R | x-ray diffraction | A | — | — |
| 6UY7 | Crystal structure of the STAC3 tandem SH3 domains - P269R | x-ray diffraction | A | — | — |
| 6UY8 | Crystal structure of the STAC3 tandem SH3 domains - P269R, K329N | x-ray diffraction | A, B | CL | — |
| 6UY8 | Crystal structure of the STAC3 tandem SH3 domains - P269R, K329N | x-ray diffraction | A, B | CL | — |
| 6UY9 | Crystal structure of the STAC3 tandem SH3 domains - P269R, W284S | x-ray diffraction | A | NA | — |
| 6UY9 | Crystal structure of the STAC3 tandem SH3 domains - P269R, W284S | x-ray diffraction | A | NA | — |
| Q96MF2 | AlphaFold monomer V2.0 prediction for SH3 and cysteine-rich domain- containing protein 3 (Q96MF2) | predicted | A | — | 4 (best 0.69) |
Ligands
Experiment against prediction
- 6UY8 chain B against the predicted model Q96MF2: TM-score 0.98, RMSD 0.55 Å
- 6UY8 chain B against the predicted model Q96MF2: TM-score 0.98, RMSD 0.55 Å
- 6B29 chain A against the predicted model Q96MF2: TM-score 0.98, RMSD 0.47 Å
- 6B29 chain B against the predicted model Q96MF2: TM-score 0.96, RMSD 0.62 Å
- 6UY7 chain A against the predicted model Q96MF2: TM-score 0.96, RMSD 0.81 Å
- 6UY7 chain A against the predicted model Q96MF2: TM-score 0.96, RMSD 0.81 Å
- 6UY9 chain A against the predicted model Q96MF2: TM-score 0.95, RMSD 1.25 Å
- 6UY9 chain A against the predicted model Q96MF2: TM-score 0.95, RMSD 1.25 Å
- 6UY8 chain A against the predicted model Q96MF2: TM-score 0.93, RMSD 1.49 Å
- 6UY8 chain A against the predicted model Q96MF2: TM-score 0.93, RMSD 1.49 Å
Elsewhere
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