MolNFT v1 · #438775 · protein
AlphaFold monomer V2.0 prediction for RNA polymerase II subunit a C-terminal domain phosphatase SSU72 (Q9NP77)
Q9NP77: “AlphaFold monomer V2.0 prediction for RNA polymerase II subunit a C-terminal domain phosphatase SSU72 (Q9NP77)”. 2 pockets (best druggability 0.36). MolNFT v1 #438775 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9NP77
- Type
- protein
- Length
- 194 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4088355aDE653eFFBf918F33FB6255eb7455757E
- Molecule
- RNA polymerase II subunit a C-terminal domain phosphatase SSU72
- UniProt
- Q9NP77
- Pockets
- 2 · best druggability 0.36
Structure
1 distinct chain · 47% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA polymerase II subunit a C-terminal domain phosphatase SSU72 | protein | 194 | 47% helix, 19% strand | Q9NP77 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 85 | 0.36 | 0.76 | 19 | empty |
| 2 | 75 | 0.34 | 0.76 | 17 | empty |
Compared structures
- 4H3H · Crystal structure of a ternary complex of human symplekin ntd, human SSU72 and a RNA… · an experimental structure of the same protein · chain A against E, TM-score 0.98
- 4H3H · Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA… · an experimental structure of the same protein · chain A against E, TM-score 0.98
- 3O2Q · Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex · an experimental structure of the same protein · chain A against E, TM-score 0.98
- 3O2Q · Crystal structure of the human symplekin-SSU72-ctd phosphopeptide complex · an experimental structure of the same protein · chain A against E, TM-score 0.98
- 4H3K · Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA… · an experimental structure of the same protein · chain A against E, TM-score 0.98
- 4H3K · Crystal structure of a ternary complex of human symplekin ntd, human SSU72 and a RNA… · an experimental structure of the same protein · chain A against E, TM-score 0.98
- 3O2S · Crystal structure of the human symplekin-Ssu72 complex · an experimental structure of the same protein · chain A against B, TM-score 0.97
- 3O2S · Crystal structure of the human symplekin-SSU72 complex · an experimental structure of the same protein · chain A against B, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NP77
- Elsewhere: UniProt Q9NP77 · AlphaFold DB Q9NP77
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