UniProt Q9NP77
RNA polymerase II subunit a C-terminal domain phosphatase SSU72 (Q9NP77)
RNA polymerase II subunit a C-terminal domain phosphatase SSU72 (UniProt Q9NP77): 8 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q9NP77
- Protein
- RNA polymerase II subunit a C-terminal domain phosphatase SSU72
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
9 records of Q9NP77 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3O2Q | Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex | x-ray diffraction | B, E | — | — |
| 3O2Q | Crystal structure of the human symplekin-SSU72-ctd phosphopeptide complex | x-ray diffraction | B, E | — | — |
| 3O2S | Crystal structure of the human symplekin-Ssu72 complex | x-ray diffraction | B | — | — |
| 3O2S | Crystal structure of the human symplekin-SSU72 complex | x-ray diffraction | B | — | — |
| 4H3H | Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA poymerase II… | x-ray diffraction | B, E | — | — |
| 4H3H | Crystal structure of a ternary complex of human symplekin ntd, human SSU72 and a RNA poymerase II… | x-ray diffraction | B, E | — | — |
| 4H3K | Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA polymerase II… | x-ray diffraction | B, E | — | — |
| 4H3K | Crystal structure of a ternary complex of human symplekin ntd, human SSU72 and a RNA polymerase II… | x-ray diffraction | B, E | — | — |
| Q9NP77 | AlphaFold monomer V2.0 prediction for RNA polymerase II subunit a C-terminal domain phosphatase… | predicted | A | — | 2 (best 0.36) |
Experiment against prediction
- 4H3K chain E against the predicted model Q9NP77: TM-score 1.00, RMSD 0.26 Å
- 4H3K chain E against the predicted model Q9NP77: TM-score 1.00, RMSD 0.26 Å
- 4H3H chain E against the predicted model Q9NP77: TM-score 0.99, RMSD 0.42 Å
- 4H3H chain E against the predicted model Q9NP77: TM-score 0.99, RMSD 0.42 Å
- 3O2Q chain E against the predicted model Q9NP77: TM-score 0.99, RMSD 0.42 Å
- 3O2Q chain E against the predicted model Q9NP77: TM-score 0.99, RMSD 0.42 Å
- 3O2S chain B against the predicted model Q9NP77: TM-score 0.99, RMSD 0.56 Å
- 3O2S chain B against the predicted model Q9NP77: TM-score 0.99, RMSD 0.56 Å
- 4H3K chain B against the predicted model Q9NP77: TM-score 0.98, RMSD 0.70 Å
- 4H3K chain B against the predicted model Q9NP77: TM-score 0.98, RMSD 0.70 Å
Elsewhere
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