MolNFT v1 · #436379 · protein

AlphaFold monomer V2.0 prediction for inner nuclear membrane protein SRC1 (Q03707)

Q03707: “AlphaFold monomer V2.0 prediction for inner nuclear membrane protein SRC1 (Q03707)”. 5 pockets (best druggability 0.71). MolNFT v1 #436379 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q03707
Type: protein
Length: 834 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xAcde31F011Da58757068544bc9B82f37d30d5Bf0
Molecule: Inner nuclear membrane protein SRC1
UniProt: Q03707
Pockets: 5 · best druggability 0.71

Structure

1 distinct chain · 32% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Inner nuclear membrane protein SRC1	protein	834	32% helix, 6% strand	Q03707

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	628	0.71	0.78	54	empty
2	90	0.35	0.75	18	empty
3	54	0.29	0.75	12	empty
4	61	0.28	0.73	15	empty
5	65	0.27	0.72	11	empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

4XZR · Structure of yeast importin a bound to the membrane protein nuclear localization signal… · an experimental structure of the same protein · chain A against A, TM-score 0.02
4XZR · Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal… · an experimental structure of the same protein · chain A against A, TM-score 0.02

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q03707
Elsewhere: UniProt Q03707 · AlphaFold DB Q03707

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