MolNFT v1 · #436343 · protein
AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 12 (Q6BUQ1)
Q6BUQ1: “AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 12 (Q6BUQ1)”. 19 pockets (best druggability 0.82). MolNFT v1 #436343 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6BUQ1
- Type
- protein
- Length
- 1,661 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x429aA010A80A47FF4a2777bB34A2bba144d19df2
- Molecule
- Mediator of RNA polymerase II transcription subunit 12
- UniProt
- Q6BUQ1
- Pockets
- 19 · best druggability 0.82
Structure
1 distinct chain · 58% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mediator of RNA polymerase II transcription subunit 12 | protein | 1661 | 58% helix, 2% strand | Q6BUQ1 |
Pockets
19 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 922 | 0.82 | 0.84 | 97 | empty |
| 2 | 1032 | 0.78 | 0.80 | 75 | empty |
| 3 | 1066 | 0.76 | 0.78 | 93 | empty |
| 4 | 464 | 0.71 | 0.81 | 48 | empty |
| 5 | 712 | 0.68 | 0.75 | 51 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6BUQ1
- Elsewhere: UniProt Q6BUQ1 · AlphaFold DB Q6BUQ1
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