Research workbench
AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 12 (Q6BUQ1)
Analyse AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q6BUQ1
- Type
- protein
- Length
- 1,661 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x429aA010A80A47FF4a2777bB34A2bba144d19df2
- Molecule
- Mediator of RNA polymerase II transcription subunit 12
- UniProt
- Q6BUQ1
- Pockets
- 19 · best druggability 0.82
Structure
1 distinct chain · 58% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mediator of RNA polymerase II transcription subunit 12 | protein | 1661 | 58% helix, 2% strand | Q6BUQ1 |
Pockets
19 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 922 | 0.82 | 0.84 | 97 | empty |
| 2 | 1032 | 0.78 | 0.80 | 75 | empty |
| 3 | 1066 | 0.76 | 0.78 | 93 | empty |
| 4 | 464 | 0.71 | 0.81 | 48 | empty |
| 5 | 712 | 0.68 | 0.75 | 51 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6BUQ1
- Elsewhere: UniProt Q6BUQ1 · AlphaFold DB Q6BUQ1
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