MolNFT v1 · #432894 · protein
AlphaFold monomer V2.0 prediction for sortilin-related receptor (O88307)
O88307: “AlphaFold monomer V2.0 prediction for sortilin-related receptor (O88307)”. 20 pockets (best druggability 0.77). MolNFT v1 #432894 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O88307
- Type
- protein
- Length
- 2,215 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB44F19a0cb161828322eEEd13F55d4C3C34938d2
- Molecule
- Sortilin-related receptor
- UniProt
- O88307
- Pockets
- 20 · best druggability 0.77
Structure
1 distinct chain · 4% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sortilin-related receptor | protein | 2215 | 4% helix, 37% strand | O88307 |
Pockets
20 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 374 | 0.77 | 0.87 | 48 | empty |
| 2 | 389 | 0.66 | 0.79 | 57 | empty |
| 3 | 91 | 0.63 | 0.89 | 14 | empty |
| 4 | 137 | 0.61 | 0.85 | 24 | empty |
| 5 | 120 | 0.54 | 0.82 | 24 | empty |
Modifications
Observed in the structure: 44 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O88307
- Elsewhere: UniProt O88307 · AlphaFold DB O88307
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