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AlphaFold monomer V2.0 prediction for sortilin-related receptor (O88307)

Analyse AlphaFold monomer V2.0 prediction for sortilin-related receptor (O88307) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
O88307
Type
protein
Length
2,215 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xB44F19a0cb161828322eEEd13F55d4C3C34938d2
Molecule
Sortilin-related receptor
UniProt
O88307
Pockets
20 · best druggability 0.77

Structure

1 distinct chain · 4% helix, 37% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASortilin-related receptorprotein22154% helix, 37% strandO88307

Pockets

20 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13740.770.8748empty
23890.660.7957empty
3910.630.8914empty
41370.610.8524empty
51200.540.8224empty

Modifications

Observed in the structure: 44 disulfide (disulfide).

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