MolNFT v1 · #431993 · protein

AlphaFold monomer V2.0 prediction for sorting nexin-25 (Q9H3E2)

Q9H3E2: “AlphaFold monomer V2.0 prediction for sorting nexin-25 (Q9H3E2)”. 11 pockets (best druggability 0.75). MolNFT v1 #431993 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9H3E2
Type: protein
Length: 840 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
Molecule: Sorting nexin-25
UniProt: Q9H3E2
Pockets: 11 · best druggability 0.75

Structure

1 distinct chain · 65% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sorting nexin-25	protein	840	65% helix, 4% strand	Q9H3E2

Pockets

11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	888	0.75	0.77	51	empty
2	198	0.63	0.83	32	empty
3	453	0.61	0.76	41	empty
4	202	0.51	0.77	24	empty
5	128	0.46	0.77	17	empty

Compared structures

5WOE · Solution structure of the sorting nexin 25 phox-homology domain · an experimental structure of the same protein · chain A against A, TM-score 0.14

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9H3E2
Elsewhere: UniProt Q9H3E2 · AlphaFold DB Q9H3E2

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.