Research workbench
AlphaFold monomer V2.0 prediction for sorting nexin-25 (Q9H3E2)
Analyse AlphaFold monomer V2.0 prediction for sorting nexin-25 (Q9H3E2) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9H3E2
- Type
- protein
- Length
- 840 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
- Molecule
- Sorting nexin-25
- UniProt
- Q9H3E2
- Pockets
- 11 · best druggability 0.75
Structure
1 distinct chain · 65% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sorting nexin-25 | protein | 840 | 65% helix, 4% strand | Q9H3E2 |
Pockets
11 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 888 | 0.75 | 0.77 | 51 | empty |
| 2 | 198 | 0.63 | 0.83 | 32 | empty |
| 3 | 453 | 0.61 | 0.76 | 41 | empty |
| 4 | 202 | 0.51 | 0.77 | 24 | empty |
| 5 | 128 | 0.46 | 0.77 | 17 | empty |
Compared structures
- 5WOE · Solution structure of the sorting nexin 25 phox-homology domain · an experimental structure of the same protein · chain A against A, TM-score 0.14
- 5WOE · Solution structure of the sorting nexin 25 phox-homology domain · an experimental structure of the same protein · chain A against A, TM-score 0.14
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H3E2
- Elsewhere: UniProt Q9H3E2 · AlphaFold DB Q9H3E2
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