MolNFT v1 · #431960 · protein

AlphaFold monomer V2.0 prediction for sorting nexin-16 (P57768)

P57768: “AlphaFold monomer V2.0 prediction for sorting nexin-16 (P57768)”. 3 pockets (best druggability 0.54). MolNFT v1 #431960 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P57768
Type: protein
Length: 344 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xc0F878C3f3E2a1874e2A6daC80d429e553DdB0D5
Molecule: Sorting nexin-16
UniProt: P57768
Pockets: 3 · best druggability 0.54

Structure

1 distinct chain · 29% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sorting nexin-16	protein	344	29% helix, 7% strand	P57768

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	302	0.54	0.75	26	empty
2	114	0.44	0.77	12	empty
3	78	0.42	0.79	19	empty

Compared structures

5GW1 · Crystal structure of SNX16 px-coiled coil in space group P212121 · an experimental structure of the same protein · chain A against A, TM-score 0.39
5GW0 · Crystal structure of SNX16 px-coiled coil · an experimental structure of the same protein · chain A against D, TM-score 0.38

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P57768
Elsewhere: UniProt P57768 · AlphaFold DB P57768

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