MolNFT v1 · #431893 · protein
AlphaFold monomer V2.0 prediction for gamma-2-syntrophin (Q9NY99)
Q9NY99: “AlphaFold monomer V2.0 prediction for gamma-2-syntrophin (Q9NY99)”. 8 pockets (best druggability 0.72). MolNFT v1 #431893 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9NY99
- Type
- protein
- Length
- 539 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x8d96d6Ee1CD7B2e188d9779006d86D77205A1292
- Molecule
- Gamma-2-syntrophin
- UniProt
- Q9NY99
- Pockets
- 8 · best druggability 0.72
Structure
1 distinct chain · 23% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Gamma-2-syntrophin | protein | 539 | 23% helix, 34% strand | Q9NY99 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 359 | 0.72 | 0.84 | 48 | empty |
| 2 | 604 | 0.70 | 0.78 | 40 | empty |
| 3 | 121 | 0.54 | 0.82 | 21 | empty |
| 4 | 130 | 0.50 | 0.79 | 19 | empty |
| 5 | 84 | 0.49 | 0.83 | 19 | empty |
Compared structures
- 7QQL · The PDZ domain of SNTG2 complexed with the phosphorylated PDZ-binding motif of RSK1 · an experimental structure of the same protein · chain A against C, TM-score 0.22
- 7QQL · The PDZ domain of SNTG2 complexed with the phosphorylated PDZ-binding motif of RSK1 · an experimental structure of the same protein · chain A against C, TM-score 0.22
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NY99
- Elsewhere: UniProt Q9NY99 · AlphaFold DB Q9NY99
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