GL1X · GenesisL1 explorer

MolNFT v1 · #431873 · protein

AlphaFold monomer V2.0 prediction for U1 small nuclear ribonucleoprotein a (Q06AA4)

Q06AA4: “AlphaFold monomer V2.0 prediction for U1 small nuclear ribonucleoprotein a (Q06AA4)”. 2 pockets (best druggability 0.45). MolNFT v1 #431873 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q06AA4
Type
protein
Length
282 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xd10960F956646DE8b64d3598984c91C2d5Af3D7b
Molecule
U1 small nuclear ribonucleoprotein a
UniProt
Q06AA4
Pockets
2 · best druggability 0.45

Structure

1 distinct chain · 19% helix, 18% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AU1 small nuclear ribonucleoprotein aprotein28219% helix, 18% strandQ06AA4

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1530.450.8313empty
2730.310.7418empty

Compared structures

  • 4PKD · U1-70k in complex with U1 snRNA stem-loops 1 and U1-A RRM in complex with stem-loop 2 · an experimental structure of the same protein · chain A against B, TM-score 0.35
  • 4PKD · U1-70K in complex with U1 snrna stem-loops 1 and U1-a rrm in complex with stem-loop 2 · an experimental structure of the same protein · chain A against B, TM-score 0.35

Analyse

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