MolNFT v1 · #428915 · protein
AlphaFold monomer V2.0 prediction for nucleotide exchange factor SIL1 (Q08199)
Q08199: “AlphaFold monomer V2.0 prediction for nucleotide exchange factor SIL1 (Q08199)”. 3 pockets (best druggability 0.45). MolNFT v1 #428915 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q08199
- Type
- protein
- Length
- 421 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x416EFBd88c1C583c8Cc036402f23fEaB492EB175
- Molecule
- Nucleotide exchange factor SIL1
- UniProt
- Q08199
- Pockets
- 3 · best druggability 0.45
Structure
1 distinct chain · 53% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleotide exchange factor SIL1 | protein | 421 | 53% helix, 6% strand | Q08199 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 171 | 0.45 | 0.75 | 28 | empty |
| 2 | 135 | 0.37 | 0.72 | 24 | empty |
| 3 | 52 | 0.28 | 0.74 | 9 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 3QML · The structural analysis of Sil1-Bip complex reveals the mechanism for Sil1 to function as… · an experimental structure of the same protein · chain A against D, TM-score 0.64
- 3QML · The structural analysis of SIL1-bip complex reveals the mechanism for SIL1 to function as… · an experimental structure of the same protein · chain A against D, TM-score 0.64
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q08199
- Elsewhere: UniProt Q08199 · AlphaFold DB Q08199
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