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AlphaFold monomer V2.0 prediction for nucleotide exchange factor SIL1 (Q08199)

Analyse AlphaFold monomer V2.0 prediction for nucleotide exchange factor SIL1 (Q08199) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: Q08199
Type: protein
Length: 421 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x416EFBd88c1C583c8Cc036402f23fEaB492EB175
Molecule: Nucleotide exchange factor SIL1
UniProt: Q08199
Pockets: 3 · best druggability 0.45

Structure

1 distinct chain · 53% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleotide exchange factor SIL1	protein	421	53% helix, 6% strand	Q08199

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	171	0.45	0.75	28	empty
2	135	0.37	0.72	24	empty
3	52	0.28	0.74	9	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

3QML · The structural analysis of Sil1-Bip complex reveals the mechanism for Sil1 to function as… · an experimental structure of the same protein · chain A against D, TM-score 0.64
3QML · The structural analysis of SIL1-bip complex reveals the mechanism for SIL1 to function as… · an experimental structure of the same protein · chain A against D, TM-score 0.64

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q08199
Elsewhere: UniProt Q08199 · AlphaFold DB Q08199

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