MolNFT v1 · #425861 · protein

AlphaFold monomer V2.0 prediction for semaphorin-6C (Q9WTL3)

Q9WTL3: “AlphaFold monomer V2.0 prediction for semaphorin-6C (Q9WTL3)”. 5 pockets (best druggability 0.76). MolNFT v1 #425861 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9WTL3
Type: protein
Length: 960 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x5e58272ea25a05e06901A2eAe9f63939b344e0c6
Molecule: Semaphorin-6C
UniProt: Q9WTL3
Pockets: 5 · best druggability 0.76

Structure

1 distinct chain · 12% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Semaphorin-6C	protein	960	12% helix, 22% strand	Q9WTL3

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1184	0.76	0.78	95	empty
2	241	0.56	0.78	34	empty
3	163	0.42	0.74	27	empty
4	94	0.41	0.77	14	empty
5	70	0.31	0.74	17	empty

Modifications

Observed in the structure: 8 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9WTL3
Elsewhere: UniProt Q9WTL3 · AlphaFold DB Q9WTL3

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