MolNFT v1 · #423500 · protein

AlphaFold monomer V2.0 prediction for exocyst complex component SEC8 (P32855)

P32855: “AlphaFold monomer V2.0 prediction for exocyst complex component SEC8 (P32855)”. 17 pockets (best druggability 0.66). MolNFT v1 #423500 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P32855
Type: protein
Length: 1,065 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xa73BAb1DabE4333A884D03393eAa10c3B4215494
Molecule: Exocyst complex component SEC8
UniProt: P32855
Pockets: 17 · best druggability 0.66

Structure

1 distinct chain · 67% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Exocyst complex component SEC8	protein	1065	67% helix, 1% strand	P32855

Pockets

17 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	560	0.66	0.77	59	empty
2	160	0.62	0.84	28	empty
3	143	0.59	0.84	21	empty
4	101	0.55	0.84	20	empty
5	191	0.51	0.77	26	empty

Compared structures

5YFP · Cryo-EM Structure of the Exocyst Complex · an experimental structure of the same protein · chain A against D, TM-score 0.65
5YFP · Cryo-EM structure of the exocyst complex · an experimental structure of the same protein · chain A against D, TM-score 0.65
6VKL · Negative stain reconstruction of the yeast exocyst octameric complex. · an experimental structure of the same protein · chain A against D, TM-score 0.65

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P32855
Elsewhere: UniProt P32855 · AlphaFold DB P32855

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