GL1X · GenesisL1 explorer

MolNFT v1 · #423475 · protein

AlphaFold monomer V2.0 prediction for protein translocation protein SEC63 (P14906)

P14906: “AlphaFold monomer V2.0 prediction for protein translocation protein SEC63 (P14906)”. 2 pockets (best druggability 0.45). MolNFT v1 #423475 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P14906
Type
protein
Length
663 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x35612D34a32C306CA4fc1edA9360D1F717e25950
Molecule
Protein translocation protein SEC63
UniProt
P14906
Pockets
2 · best druggability 0.45

Structure

1 distinct chain · 48% helix, 11% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProtein translocation protein SEC63protein66348% helix, 11% strandP14906

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1560.450.8422empty
2700.410.8015empty

Compared structures

  • 7KAP · Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with… · an experimental structure of the same protein · chain A against D, TM-score 0.69
  • 7KAP · Cryo-EM structure of the sec complex from S. cerevisiae, SEC61 pore mutant, class with… · an experimental structure of the same protein · chain A against D, TM-score 0.69
  • 7KAI · Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class with Sec62… · an experimental structure of the same protein · chain A against D, TM-score 0.69
  • 7KAI · Cryo-EM structure of the sec complex from S. cerevisiae, wild-type, class with SEC62… · an experimental structure of the same protein · chain A against D, TM-score 0.69
  • 7KAO · Cryo-EM structure of the sec complex from S. cerevisiae, SEC61 pore mutant, class without… · an experimental structure of the same protein · chain A against D, TM-score 0.69
  • 7KAO · Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class without… · an experimental structure of the same protein · chain A against D, TM-score 0.69
  • 7KAH · Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class without Sec62 · an experimental structure of the same protein · chain A against D, TM-score 0.68
  • 7KAH · Cryo-EM structure of the sec complex from S. cerevisiae, wild-type, class without SEC62 · an experimental structure of the same protein · chain A against D, TM-score 0.68
  • 7KAJ · Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class with Sec62… · an experimental structure of the same protein · chain A against D, TM-score 0.68
  • 7KAJ · Cryo-EM structure of the sec complex from S. cerevisiae, wild-type, class with SEC62… · an experimental structure of the same protein · chain A against D, TM-score 0.68
  • 7KAQ · Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with… · an experimental structure of the same protein · chain A against D, TM-score 0.68
  • 7KAQ · Cryo-EM structure of the sec complex from S. cerevisiae, SEC61 pore mutant, class with… · an experimental structure of the same protein · chain A against D, TM-score 0.68

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