UniProt P14906
Protein translocation protein SEC63 (P14906)
Protein translocation protein SEC63 (UniProt P14906): 28 experimental structures and 1 predicted model on GenesisL1, 153 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P14906
- Protein
- Protein translocation protein SEC63
- Experimental structures
- 28
- Predicted models
- 1
- Pockets
- 153 · 13 records with a druggable one
Structures
29 records of P14906 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6N3Q | Cryo-EM structure of the yeast Sec complex | electron microscopy | D | — | 11 (best 0.85) |
| 6N3Q | Cryo-EM structure of the yeast sec complex | electron microscopy | D | — | — |
| 6ND1 | CryoEM structure of the Sec Complex from yeast | electron microscopy | A | — | — |
| 6ND1 | Cryoem structure of the sec complex from yeast | electron microscopy | A | — | — |
| 7AFT | Cryo-EM structure of the signal sequence-engaged post-translational Sec translocon | electron microscopy | D | — | 9 (best 0.82) |
| 7AFT | Cryo-EM structure of the signal sequence-engaged post-translational sec translocon | electron microscopy | D | — | — |
| 7KAH | Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class without Sec62 | electron microscopy | D | — | 13 (best 0.83) |
| 7KAH | Cryo-EM structure of the sec complex from S. cerevisiae, wild-type, class without SEC62 | electron microscopy | D | — | — |
| 7KAI | Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class with Sec62, conformation… | electron microscopy | D | — | 11 (best 0.83) |
| 7KAI | Cryo-EM structure of the sec complex from S. cerevisiae, wild-type, class with SEC62, conformation… | electron microscopy | D | — | — |
| 7KAJ | Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class with Sec62, conformation… | electron microscopy | D | — | 14 (best 0.83) |
| 7KAJ | Cryo-EM structure of the sec complex from S. cerevisiae, wild-type, class with SEC62, conformation… | electron microscopy | D | — | — |
| 7KAO | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class without Sec62 | electron microscopy | D | — | 13 (best 0.85) |
| 7KAO | Cryo-EM structure of the sec complex from S. cerevisiae, SEC61 pore mutant, class without SEC62 | electron microscopy | D | — | — |
| 7KAP | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with Sec62… | electron microscopy | D | — | 10 (best 0.84) |
| 7KAP | Cryo-EM structure of the sec complex from S. cerevisiae, SEC61 pore mutant, class with SEC62… | electron microscopy | D | — | — |
| 7KAQ | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with Sec62… | electron microscopy | D | — | 11 (best 0.85) |
| 7KAQ | Cryo-EM structure of the sec complex from S. cerevisiae, SEC61 pore mutant, class with SEC62… | electron microscopy | D | — | — |
| 7KAR | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec63 FN3 mutant, class without Sec62 | electron microscopy | D | — | 13 (best 0.83) |
| 7KAR | Cryo-EM structure of the sec complex from S. cerevisiae, SEC63 FN3 mutant, class without SEC62 | electron microscopy | D | — | — |
| 7KAS | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec63 FN3 mutant, class with Sec62 | electron microscopy | D | — | 10 (best 0.83) |
| 7KAS | Cryo-EM structure of the sec complex from S. cerevisiae, SEC63 FN3 mutant, class with SEC62 | electron microscopy | D | — | — |
| 7KAT | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore ring and Sec63 FN3 double… | electron microscopy | D | — | 12 (best 0.84) |
| 7KAT | Cryo-EM structure of the sec complex from S. cerevisiae, SEC61 pore ring and SEC63 FN3 double… | electron microscopy | D | — | — |
| 7KAU | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore ring and Sec63 FN3 double… | electron microscopy | D | — | 14 (best 0.84) |
| 7KAU | Cryo-EM structure of the sec complex from S. cerevisiae, SEC61 pore ring and SEC63 FN3 double… | electron microscopy | D | — | — |
| 7KB5 | Cryo-EM structure of the Sec complex from yeast, Sec63 FN3 and residues 210-216 mutated | electron microscopy | D | — | 10 (best 0.84) |
| 7KB5 | Cryo-EM structure of the sec complex from yeast, SEC63 FN3 and residues 210-216 mutated | electron microscopy | D | — | — |
| P14906 | AlphaFold monomer V2.0 prediction for protein translocation protein SEC63 (P14906) | predicted | A | — | 2 (best 0.45) |
Experiment against prediction
- 7KB5 chain D against the predicted model P14906: TM-score 0.95, RMSD 2.05 Å
- 7KB5 chain D against the predicted model P14906: TM-score 0.95, RMSD 2.05 Å
- 6ND1 chain A against the predicted model P14906: TM-score 0.92, RMSD 2.54 Å
- 6ND1 chain A against the predicted model P14906: TM-score 0.92, RMSD 2.54 Å
- 7KAP chain D against the predicted model P14906: TM-score 0.91, RMSD 2.57 Å
- 7KAP chain D against the predicted model P14906: TM-score 0.91, RMSD 2.57 Å
- 7KAI chain D against the predicted model P14906: TM-score 0.91, RMSD 2.60 Å
- 7KAI chain D against the predicted model P14906: TM-score 0.91, RMSD 2.60 Å
- 6N3Q chain D against the predicted model P14906: TM-score 0.91, RMSD 2.62 Å
- 6N3Q chain D against the predicted model P14906: TM-score 0.91, RMSD 2.62 Å
Elsewhere
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