MolNFT v1 · #422548 · protein
AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor SDC25 (C8ZCV7)
C8ZCV7: “AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor SDC25 (C8ZCV7)”. 16 pockets (best druggability 0.72). MolNFT v1 #422548 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- C8ZCV7
- Type
- protein
- Length
- 1,252 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xFfa14EF9812cbceCFF953A0e1f923941F78cc638
- Molecule
- Guanine nucleotide exchange factor SDC25
- UniProt
- C8ZCV7
- Pockets
- 16 · best druggability 0.72
Structure
1 distinct chain · 47% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Guanine nucleotide exchange factor SDC25 | protein | 1252 | 47% helix, 6% strand | C8ZCV7 |
Pockets
16 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 831 | 0.72 | 0.77 | 76 | empty |
| 2 | 762 | 0.71 | 0.77 | 57 | empty |
| 3 | 55 | 0.70 | 0.97 | 15 | empty |
| 4 | 523 | 0.68 | 0.78 | 40 | empty |
| 5 | 645 | 0.66 | 0.76 | 71 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C8ZCV7
- Elsewhere: UniProt C8ZCV7 · AlphaFold DB C8ZCV7
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