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AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor SDC25 (C8ZCV7)

Analyse AlphaFold monomer V2.0 prediction for guanine nucleotide exchange factor SDC25… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
C8ZCV7
Type
protein
Length
1,252 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xFfa14EF9812cbceCFF953A0e1f923941F78cc638
Molecule
Guanine nucleotide exchange factor SDC25
UniProt
C8ZCV7
Pockets
16 · best druggability 0.72

Structure

1 distinct chain · 47% helix, 6% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGuanine nucleotide exchange factor SDC25protein125247% helix, 6% strandC8ZCV7

Pockets

16 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18310.720.7776empty
27620.710.7757empty
3550.700.9715empty
45230.680.7840empty
56450.660.7671empty

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