MolNFT v1 · #421495 · protein

AlphaFold monomer V2.0 prediction for sodium channel protein type 2 subunit alpha (B1AWN6)

B1AWN6: “AlphaFold monomer V2.0 prediction for sodium channel protein type 2 subunit alpha (B1AWN6)”. 20 pockets (best druggability 0.86). MolNFT v1 #421495 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: B1AWN6
Type: protein
Length: 2,006 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xb3c0C983Fc44934AC589D7131C08a72544EBB92E
Molecule: Sodium channel protein type 2 subunit alpha
UniProt: B1AWN6
Pockets: 20 · best druggability 0.86

Structure

1 distinct chain · 52% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sodium channel protein type 2 subunit alpha	protein	2006	52% helix, 3% strand	B1AWN6

Pockets

20 pockets found on a 1 Å grid, 16 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1085	0.86	0.86	97	empty
2	819	0.73	0.78	55	empty
3	1099	0.72	0.76	93	empty
4	506	0.68	0.79	45	empty
5	323	0.66	0.81	46	empty

Modifications

Observed in the structure: 6 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B1AWN6
Elsewhere: UniProt B1AWN6 · AlphaFold DB B1AWN6

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