MolNFT v1 · #421492 · protein

AlphaFold monomer V2.0 prediction for sodium channel protein 1 brain (Q05973)

Q05973: “AlphaFold monomer V2.0 prediction for sodium channel protein 1 brain (Q05973)”. 20 pockets (best druggability 0.82). MolNFT v1 #421492 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q05973
Type: protein
Length: 1,522 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x5dC362867B8F1D91BcF4e783Db45bC54097cA2a4
Molecule: Sodium channel protein 1 brain
UniProt: Q05973
Pockets: 20 · best druggability 0.82

Structure

1 distinct chain · 65% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sodium channel protein 1 brain	protein	1522	65% helix, 4% strand	Q05973

Pockets

20 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1191	0.82	0.83	111	empty
2	717	0.75	0.80	58	empty
3	1158	0.74	0.77	105	empty
4	528	0.71	0.79	61	empty
5	638	0.70	0.77	68	empty

Modifications

Observed in the structure: 5 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q05973
Elsewhere: UniProt Q05973 · AlphaFold DB Q05973

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