GL1X · GenesisL1 explorer

MolNFT v1 · #421320 · protein

AlphaFold monomer V2.0 prediction for kit ligand (P20826)

P20826: “AlphaFold monomer V2.0 prediction for kit ligand (P20826)”. 1 pocket (best druggability 0.32). MolNFT v1 #421320 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P20826
Type
protein
Length
273 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x71cEF7DAfDD84b59FAEbC7E165BEeDf9b251ccF8
Molecule
Kit ligand
UniProt
P20826
Pockets
1 · best druggability 0.32

Structure

1 distinct chain · 59% helix, 4% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AKit ligandprotein27359% helix, 4% strandP20826

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1540.320.7711empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

  • 2O26 · Structure of a class III rtk signaling assembly · an experimental structure of the same protein · chain A against B, TM-score 0.47
  • 2O26 · Structure of a class III RTK signaling assembly · an experimental structure of the same protein · chain A against B, TM-score 0.47
  • 2O27 · Structure of a class III RTK signaling assembly · an experimental structure of the same protein · chain A against A, TM-score 0.43
  • 2O27 · Structure of a class III rtk signaling assembly · an experimental structure of the same protein · chain A against A, TM-score 0.43

Analyse

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