MolNFT v1 · #421275 · protein
AlphaFold monomer V2.0 prediction for stearoyl-CoA desaturase (O00767)
O00767: “AlphaFold monomer V2.0 prediction for stearoyl-CoA desaturase (O00767)”. 6 pockets (best druggability 0.80). MolNFT v1 #421275 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O00767
- Type
- protein
- Length
- 359 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x69eE01C8f0EE6680BfD1adfA715C501Aba23F4B9
- Molecule
- Stearoyl-CoA desaturase
- UniProt
- O00767
- Pockets
- 6 · best druggability 0.80
Structure
1 distinct chain · 54% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Stearoyl-CoA desaturase | protein | 359 | 54% helix, 3% strand | O00767 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 177 | 0.80 | 0.96 | 40 | empty |
| 2 | 101 | 0.53 | 0.83 | 14 | empty |
| 3 | 201 | 0.52 | 0.77 | 31 | empty |
| 4 | 142 | 0.45 | 0.76 | 27 | empty |
| 5 | 83 | 0.37 | 0.76 | 12 | empty |
Compared structures
- 4ZYO · Crystal Structure of Human Integral Membrane Stearoyl-CoA Desaturase with Substrate · an experimental structure of the same protein · chain A against A, TM-score 0.80
- 4ZYO · Crystal structure of human integral membrane stearoyl-CoA desaturase with substrate · an experimental structure of the same protein · chain A against A, TM-score 0.80
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O00767
- Elsewhere: UniProt O00767 · AlphaFold DB O00767
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