MolNFT v1 · #420015 · protein

AlphaFold monomer V2.0 prediction for switch-activating protein 1 (P40847)

P40847: “AlphaFold monomer V2.0 prediction for switch-activating protein 1 (P40847)”. 1 pocket (best druggability 0.36). MolNFT v1 #420015 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P40847
Type: protein
Length: 254 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x6F7e02049B13f0f0eF041D8589c607F441790c57
Molecule: Switch-activating protein 1
UniProt: P40847
Pockets: 1 · best druggability 0.36

Structure

1 distinct chain · 60% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Switch-activating protein 1	protein	254	60% helix, 0% strand	P40847

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	104	0.36	0.74	20	empty

Compared structures

6EXT · Crystal structure of the DNA binding domain of fission yeast SAP1 · an experimental structure of the same protein · chain A against A, TM-score 0.41
6EXU · Crystal structure of the DNA binding domain of fission yeast SAP1 · an experimental structure of the same protein · chain A against A, TM-score 0.41
5JDK · Crystal structure of the DNA binding domain of SAP1 in fission yeast S.POMBE · an experimental structure of the same protein · chain A against A, TM-score 0.41
5B7J · Structure model of SAP1-DNA complex · an experimental structure of the same protein · chain A against A, TM-score 0.40

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P40847
Elsewhere: UniProt P40847 · AlphaFold DB P40847

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