GL1X · GenesisL1 explorer

MolNFT v1 · #419805 · protein

AlphaFold monomer V2.0 prediction for adenosylhomocysteinase (O51933)

O51933: “AlphaFold monomer V2.0 prediction for adenosylhomocysteinase (O51933)”. 2 pockets (best druggability 0.77). MolNFT v1 #419805 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
O51933
Type
protein
Length
404 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5c4adF1416281C09AE8eE1cbb80fF7e44cE86F97
Molecule
Adenosylhomocysteinase
UniProt
O51933
Pockets
2 · best druggability 0.77

Structure

1 distinct chain · 49% helix, 16% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AAdenosylhomocysteinaseprotein40449% helix, 16% strandO51933

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13580.770.8755empty
2980.380.7522empty

Compared structures

  • 3X2F · A Thermophilic S-Adenosylhomocysteine Hydrolase · an experimental structure of the same protein · chain A against B, TM-score 0.98
  • 3X2F · A thermophilic S-adenosylhomocysteine hydrolase · an experimental structure of the same protein · chain A against B, TM-score 0.98
  • 3X2E · A thermophilic hydrolase · an experimental structure of the same protein · chain A against A, TM-score 0.94
  • 3X2E · A thermophilic hydrolase · an experimental structure of the same protein · chain A against A, TM-score 0.94
  • 5TOV · Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from… · an experimental structure of the same protein · chain A against B, TM-score 0.94
  • 5TOV · Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from… · an experimental structure of the same protein · chain A against B, TM-score 0.94
  • 5TOW · Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from… · an experimental structure of the same protein · chain A against B, TM-score 0.94
  • 5TOW · Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from… · an experimental structure of the same protein · chain A against B, TM-score 0.94

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