UniProt O51933
Adenosylhomocysteinase (O51933)
Adenosylhomocysteinase (UniProt O51933), EC 3.3.1.1: 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O51933
- Protein
- Adenosylhomocysteinase
- EC
- 3.3.1.1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 17 · 3 records with a druggable one
Structures
9 records of O51933 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3X2E | A thermophilic hydrolase | x-ray diffraction | A, B, C, D | — | — |
| 3X2E | A thermophilic hydrolase | x-ray diffraction | A, B, C, D | — | — |
| 3X2F | A Thermophilic S-Adenosylhomocysteine Hydrolase | x-ray diffraction | A, B | — | — |
| 3X2F | A thermophilic S-adenosylhomocysteine hydrolase | x-ray diffraction | A, B | — | — |
| 5TOV | Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from Thermotoga… | x-ray diffraction | A, B | NAI, CL | 8 (best 0.85) |
| 5TOV | Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from thermotoga… | x-ray diffraction | A, B | NAI, CL | — |
| 5TOW | Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from Thermotoga… | x-ray diffraction | A, B | ADN, NAI, CL | 7 (best 0.83) |
| 5TOW | Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from thermotoga… | x-ray diffraction | A, B | ADN, NAI, CL | — |
| O51933 | AlphaFold monomer V2.0 prediction for adenosylhomocysteinase (O51933) | predicted | A | — | 2 (best 0.77) |
Ligands
Experiment against prediction
- 3X2F chain B against the predicted model O51933: TM-score 0.98, RMSD 1.04 Å
- 3X2F chain B against the predicted model O51933: TM-score 0.98, RMSD 1.04 Å
- 3X2F chain A against the predicted model O51933: TM-score 0.96, RMSD 1.41 Å
- 3X2F chain A against the predicted model O51933: TM-score 0.96, RMSD 1.41 Å
- 3X2E chain A against the predicted model O51933: TM-score 0.95, RMSD 1.81 Å
- 3X2E chain A against the predicted model O51933: TM-score 0.95, RMSD 1.81 Å
- 5TOV chain B against the predicted model O51933: TM-score 0.94, RMSD 2.01 Å
- 5TOV chain B against the predicted model O51933: TM-score 0.94, RMSD 2.01 Å
- 5TOW chain B against the predicted model O51933: TM-score 0.94, RMSD 2.04 Å
- 5TOW chain B against the predicted model O51933: TM-score 0.94, RMSD 2.04 Å
Elsewhere
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