MolNFT v1 · #419512 · protein
AlphaFold monomer V2.0 prediction for sumo-activating enzyme subunit 2 (Q9UBT2)
Q9UBT2: “AlphaFold monomer V2.0 prediction for sumo-activating enzyme subunit 2 (Q9UBT2)”. 4 pockets (best druggability 0.73). MolNFT v1 #419512 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9UBT2
- Type
- protein
- Length
- 640 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0CC4140Ba225D530b2DC080d22627144DEBB1186
- Molecule
- Sumo-activating enzyme subunit 2
- UniProt
- Q9UBT2
- Pockets
- 4 · best druggability 0.73
Structure
1 distinct chain · 38% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sumo-activating enzyme subunit 2 | protein | 640 | 38% helix, 13% strand | Q9UBT2 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1189 | 0.73 | 0.76 | 122 | empty |
| 2 | 78 | 0.38 | 0.77 | 20 | empty |
| 3 | 64 | 0.37 | 0.78 | 17 | empty |
| 4 | 92 | 0.34 | 0.74 | 14 | empty |
Compared structures
- 3KYC · Human sumo E1 complex with a SUMO1-AMP mimic · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 3KYC · Human SUMO E1 complex with a SUMO1-AMP mimic · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 1Y8Q · Sumo E1 activating enzyme SAE1-SAE2-mg-ATP complex · an experimental structure of the same protein · chain A against D, TM-score 0.80
- 1Y8Q · Sumo E1 activating enzyme SAE1-SAE2-mg-ATP complex · an experimental structure of the same protein · chain A against D, TM-score 0.80
- 1Y8R · Sumo E1 activating enzyme SAE1-SAE2-SUMO1-mg-ATP complex · an experimental structure of the same protein · chain A against E, TM-score 0.79
- 1Y8R · Sumo E1 activating enzyme SAE1-SAE2-SUMO1-mg-ATP complex · an experimental structure of the same protein · chain A against E, TM-score 0.79
- 6CWZ · Crystal structure of apo sumo E1 · an experimental structure of the same protein · chain A against D, TM-score 0.79
- 6CWZ · Crystal structure of apo SUMO E1 · an experimental structure of the same protein · chain A against D, TM-score 0.79
- 6XOG · Structure of SUMO1-ML786519 adduct bound to SAE · an experimental structure of the same protein · chain A against B, TM-score 0.77
- 6XOG · Structure of SUMO1-ML786519 adduct bound to sae · an experimental structure of the same protein · chain A against B, TM-score 0.77
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UBT2
- Elsewhere: UniProt Q9UBT2 · AlphaFold DB Q9UBT2
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