MolNFT v1 · #419433 · protein
AlphaFold monomer V2.0 prediction for nuclear mRNA export protein SAC3 (P46674)
P46674: “AlphaFold monomer V2.0 prediction for nuclear mRNA export protein SAC3 (P46674)”. 10 pockets (best druggability 0.62). MolNFT v1 #419433 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P46674
- Type
- protein
- Length
- 1,301 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x32Ca1dC302B2c5E039D1E34D7C8A8f994cACD96F
- Molecule
- Nuclear mRNA export protein SAC3
- UniProt
- P46674
- Pockets
- 10 · best druggability 0.62
Structure
1 distinct chain · 41% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nuclear mRNA export protein SAC3 | protein | 1301 | 41% helix, 5% strand | P46674 |
Pockets
10 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 440 | 0.62 | 0.76 | 37 | empty |
| 2 | 465 | 0.61 | 0.75 | 52 | empty |
| 3 | 99 | 0.50 | 0.81 | 17 | empty |
| 4 | 96 | 0.44 | 0.79 | 19 | empty |
| 5 | 142 | 0.42 | 0.75 | 22 | empty |
Compared structures
- 3T5V · Sac3:Thp1:Sem1 complex · an experimental structure of the same protein · chain A against D, TM-score 0.23
- 3T5V · SAC3:THP1:SEM1 complex · an experimental structure of the same protein · chain A against D, TM-score 0.23
- 4TRQ · Crystal structure of SAC3/THP1/SEM1 · an experimental structure of the same protein · chain A against A, TM-score 0.23
- 4TRQ · Crystal structure of Sac3/Thp1/Sem1 · an experimental structure of the same protein · chain A against A, TM-score 0.23
- 5G5P · Structure of the saccharomyces cerevisiae trex-2 complex · an experimental structure of the same protein · chain A against A, TM-score 0.23
- 5G5P · Structure of the Saccharomyces cerevisiae TREX-2 complex · an experimental structure of the same protein · chain A against A, TM-score 0.23
- 5L3T · Structure of the Saccharomyces cerevisiae TREX-2 complex · an experimental structure of the same protein · chain A against A, TM-score 0.23
- 5L3T · Structure of the saccharomyces cerevisiae trex-2 complex · an experimental structure of the same protein · chain A against A, TM-score 0.23
- 3FWC · SAC3:SUS1:CDC31 complex · an experimental structure of the same protein · chain A against F, TM-score 0.06
- 3FWC · Sac3:Sus1:Cdc31 complex · an experimental structure of the same protein · chain A against F, TM-score 0.06
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P46674
- Elsewhere: UniProt P46674 · AlphaFold DB P46674
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