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MolNFT v1 · #414861 · protein

AlphaFold monomer V2.0 prediction for 28S ribosomal protein S22, mitochondrial (P82650)

P82650: “AlphaFold monomer V2.0 prediction for 28S ribosomal protein S22, mitochondrial (P82650)”. 4 pockets (best druggability 0.52). MolNFT v1 #414861 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P82650
Type
protein
Length
360 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5e58272ea25a05e06901A2eAe9f63939b344e0c6
Molecule
28S ribosomal protein S22, mitochondrial
UniProt
P82650
Pockets
4 · best druggability 0.52

Structure

1 distinct chain · 45% helix, 4% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A28S ribosomal protein S22, mitochondrialprotein36045% helix, 4% strandP82650

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1860.520.8417empty
21090.490.8121empty
31320.410.7516empty
41320.410.7420empty

Compared structures

  • 7P2E · Human mitochondrial ribosome small subunit in complex with IF3, GMPPMP and streptomycin · an experimental structure of the same protein · chain A against R, TM-score 0.81
  • 7PO2 · Initiation complex of human mitochondrial ribosome small subunit with IF2, fMet-tRNAMet… · an experimental structure of the same protein · chain A against R, TM-score 0.81
  • 7PO1 · Initiation complex of human mitochondrial ribosome small subunit with IF3 · an experimental structure of the same protein · chain A against R, TM-score 0.81
  • 7PO3 · Human mitochondrial ribosome small subunit · an experimental structure of the same protein · chain A against R, TM-score 0.81
  • 8QRL · mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 2 · an experimental structure of the same protein · chain A against R, TM-score 0.81
  • 7PNX · Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in… · an experimental structure of the same protein · chain A against R, TM-score 0.81
  • 7PNZ · Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in… · an experimental structure of the same protein · chain A against R, TM-score 0.81
  • 7PNY · Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in… · an experimental structure of the same protein · chain A against R, TM-score 0.81
  • 7PO0 · Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in… · an experimental structure of the same protein · chain A against R, TM-score 0.81
  • 6RW4 · Structure of human mitochondrial 28S ribosome in complex with mitochondrial IF3 · an experimental structure of the same protein · chain A against R, TM-score 0.81
  • 7QI4 · Human mitochondrial ribosome at 2.2 A resolution (bound to partly built tRNAs and mRNA) · an experimental structure of the same protein · chain A against AR, TM-score 0.81
  • 7QI5 · Human mitochondrial ribosome in complex with mRNA, A/A-, P/P- and E/E-tRNAs at 2.63 A… · an experimental structure of the same protein · chain A against AR, TM-score 0.81

Analyse

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