MolNFT v1 · #393342 · protein
AlphaFold monomer V2.0 prediction for rRNA biogenesis protein RRP5 (Q05022)
Q05022: “AlphaFold monomer V2.0 prediction for rRNA biogenesis protein RRP5 (Q05022)”. 17 pockets (best druggability 0.57). MolNFT v1 #393342 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q05022
- Type
- protein
- Length
- 1,729 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf7FB783782B285Db3199EbD0D87C7bB413D7D508
- Molecule
- RRNA biogenesis protein RRP5
- UniProt
- Q05022
- Pockets
- 17 · best druggability 0.57
Structure
1 distinct chain · 28% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RRNA biogenesis protein RRP5 | protein | 1729 | 28% helix, 27% strand | Q05022 |
Pockets
17 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 213 | 0.57 | 0.80 | 26 | empty |
| 2 | 300 | 0.56 | 0.76 | 36 | empty |
| 3 | 348 | 0.54 | 0.74 | 32 | empty |
| 4 | 151 | 0.46 | 0.77 | 32 | empty |
| 5 | 84 | 0.44 | 0.80 | 20 | empty |
Compared structures
- 5NLG · RRP5 C-terminal domain · an experimental structure of the same protein · chain A against A, TM-score 0.16
- 5NLG · RRP5 C-terminal domain · an experimental structure of the same protein · chain A against A, TM-score 0.16
- 5C9S · Crystal structure of the C-terminal domain of RRP5 · an experimental structure of the same protein · chain A against B, TM-score 0.16
- 5C9S · Crystal Structure of the C-terminal domain of Rrp5 · an experimental structure of the same protein · chain A against B, TM-score 0.16
- 5WWM · Crystal structure of the TPR domain of Rrp5 · an experimental structure of the same protein · chain A against A, TM-score 0.16
- 5WWM · Crystal structure of the tpr domain of RRP5 · an experimental structure of the same protein · chain A against A, TM-score 0.16
- 5WYJ · Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1) · an experimental structure of the same protein · chain A against R2, TM-score 0.16
- 7AJU · Cryo-EM structure of the 90S-exosome super-complex (state Post-A1-exosome) · an experimental structure of the same protein · chain A against JI, TM-score 0.15
- 6ZQD · Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Post-A1 · an experimental structure of the same protein · chain A against JI, TM-score 0.15
- 7AJT · Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) · an experimental structure of the same protein · chain A against JI, TM-score 0.15
- 6ZQC · Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Pre-A1 · an experimental structure of the same protein · chain A against JI, TM-score 0.15
- 5WLC · The complete structure of the small subunit processome · an experimental structure of the same protein · chain A against NJ, TM-score 0.15
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q05022
- Elsewhere: UniProt Q05022 · AlphaFold DB Q05022
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