UniProt Q05022
rRNA biogenesis protein RRP5 (Q05022)
rRNA biogenesis protein RRP5 (UniProt Q05022): 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q05022
- Protein
- rRNA biogenesis protein RRP5
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 17 · 1 record with a druggable one
Structures
13 records of Q05022 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5C9S | Crystal Structure of the C-terminal domain of Rrp5 | x-ray diffraction | B | — | — |
| 5C9S | Crystal structure of the C-terminal domain of RRP5 | x-ray diffraction | B | — | — |
| 5NLG | RRP5 C-terminal domain | x-ray diffraction | A | — | — |
| 5NLG | RRP5 C-terminal domain | x-ray diffraction | A | — | — |
| 5WLC | The complete structure of the small subunit processome | electron microscopy | NJ | — | — |
| 5WWM | Crystal structure of the tpr domain of RRP5 | x-ray diffraction | A | SO4 | — |
| 6LQQ | Cryo-EM structure of 90S small subunit preribosomes in transition states (State B) | electron microscopy | RD | — | — |
| 6LQR | Cryo-EM structure of 90S small subunit preribosomes in transition states (State C) | electron microscopy | RD | — | — |
| 6LQS | Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) | electron microscopy | RD | — | — |
| 6LQT | Cryo-EM structure of 90S small subunit preribosomes in transition states (State E) | electron microscopy | RD | — | — |
| 6LQU | Cryo-EM structure of 90S small subunit preribosomes in transition states (State A1) | electron microscopy | RD | — | — |
| 7AJT | Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) | electron microscopy | JI | — | — |
| Q05022 | AlphaFold monomer V2.0 prediction for rRNA biogenesis protein RRP5 (Q05022) | predicted | A | — | 17 (best 0.57) |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 5NLG chain A against the predicted model Q05022: TM-score 0.99, RMSD 0.61 Å
- 5NLG chain A against the predicted model Q05022: TM-score 0.99, RMSD 0.61 Å
- 5C9S chain B against the predicted model Q05022: TM-score 0.99, RMSD 0.63 Å
- 5C9S chain B against the predicted model Q05022: TM-score 0.99, RMSD 0.63 Å
- 5WWM chain A against the predicted model Q05022: TM-score 0.99, RMSD 0.65 Å
- 7AJT chain JI against the predicted model Q05022: TM-score 0.98, RMSD 0.86 Å
- 5WLC chain NJ against the predicted model Q05022: TM-score 0.97, RMSD 0.98 Å
- 6LQU chain RD against the predicted model Q05022: TM-score 0.92, RMSD 1.87 Å
- 6LQQ chain RD against the predicted model Q05022: TM-score 0.80, RMSD 1.24 Å
- 6LQR chain RD against the predicted model Q05022: TM-score 0.80, RMSD 1.24 Å
Elsewhere
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