MolNFT v1 · #388579 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta' (Q9HWC9)
Q9HWC9: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta' (Q9HWC9)”. 15 pockets (best druggability 0.78). MolNFT v1 #388579 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9HWC9
- Type
- protein
- Length
- 1,399 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7c75F0f7d6d136A2b8D4C6C6e9b3D8a697949DF1
- Molecule
- DNA-directed RNA polymerase subunit beta'
- UniProt
- Q9HWC9
- Pockets
- 15 · best druggability 0.78
Structure
1 distinct chain · 40% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit beta' | protein | 1399 | 40% helix, 20% strand | Q9HWC9 |
Pockets
15 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 934 | 0.78 | 0.80 | 81 | empty |
| 2 | 834 | 0.74 | 0.78 | 68 | empty |
| 3 | 809 | 0.71 | 0.77 | 56 | empty |
| 4 | 639 | 0.70 | 0.77 | 38 | empty |
| 5 | 874 | 0.70 | 0.75 | 54 | empty |
Compared structures
- 7XYB · The cryo-EM structure of an AlpA-loaded complex · an experimental structure of the same protein · chain A against D, TM-score 0.89
- 7XYB · The cryo-EM structure of an alpa-loaded complex · an experimental structure of the same protein · chain A against D, TM-score 0.89
- 7XYA · The cryo-EM structure of an alpa-loading complex · an experimental structure of the same protein · chain A against D, TM-score 0.88
- 7XYA · The cryo-EM structure of an AlpA-loading complex · an experimental structure of the same protein · chain A against D, TM-score 0.88
- 7F0R · Cryo-EM structure of pseudomonas aeruginosa suta transcription activation complex · an experimental structure of the same protein · chain A against D, TM-score 0.88
- 7F0R · Cryo-EM structure of Pseudomonas aeruginosa SutA transcription activation complex · an experimental structure of the same protein · chain A against D, TM-score 0.88
- 7XL4 · Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with… · an experimental structure of the same protein · chain A against D, TM-score 0.88
- 7XL4 · Cryo-EM structure of pseudomonas aeruginosa rnap sigmas holoenzyme complexes with… · an experimental structure of the same protein · chain A against D, TM-score 0.88
- 7XL3 · Cryo-EM structure of pseudomonas aeruginosa rnap sigmas holoenzyme complexes with… · an experimental structure of the same protein · chain A against D, TM-score 0.88
- 7XL3 · Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with… · an experimental structure of the same protein · chain A against D, TM-score 0.88
- 7VF9 · Cryo-EM structure of pseudomonas aeruginosa rnap sigmas holoenzyme complexes · an experimental structure of the same protein · chain A against D, TM-score 0.88
- 7VF9 · Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes · an experimental structure of the same protein · chain A against D, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HWC9
- Elsewhere: UniProt Q9HWC9 · AlphaFold DB Q9HWC9
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