MolNFT v1 · #387426 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (P9WGY8)
P9WGY8: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (P9WGY8)”. 20 pockets (best druggability 0.74). MolNFT v1 #387426 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P9WGY8
- Type
- protein
- Length
- 1,178 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x46ba7D8374862203aBCC7166BCAa8b3039Ae12D2
- Molecule
- DNA-directed RNA polymerase subunit beta
- UniProt
- P9WGY8
- Pockets
- 20 · best druggability 0.74
Structure
1 distinct chain · 27% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit beta | protein | 1178 | 27% helix, 26% strand | P9WGY8 |
Pockets
20 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 612 | 0.74 | 0.81 | 63 | empty |
| 2 | 63 | 0.70 | 0.97 | 22 | empty |
| 3 | 390 | 0.66 | 0.80 | 68 | empty |
| 4 | 257 | 0.64 | 0.82 | 32 | empty |
| 5 | 357 | 0.63 | 0.79 | 36 | empty |
Compared structures
- 7RWI · Mycobacterium tuberculosis RNA polymerase sigma L holoenzyme open promoter complex… · an experimental structure of the same protein · chain A against C, TM-score 0.94
- 6TYE · Crystal structure of MTB sigma L transcription initiation complex with 5 nt long RNA… · an experimental structure of the same protein · chain A against C, TM-score 0.94
- 6TYE · Crystal structure of mtb sigma L transcription initiation complex with 5 nt long RNA… · an experimental structure of the same protein · chain A against C, TM-score 0.94
- 6TYG · Crystal structure of mtb sigma L transcription initiation complex with 9 nt long RNA… · an experimental structure of the same protein · chain A against C, TM-score 0.94
- 6TYF · Crystal structure of mtb sigma L transcription initiation complex with 6 nt long RNA… · an experimental structure of the same protein · chain A against C, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P9WGY8
- Elsewhere: UniProt P9WGY8 · AlphaFold DB P9WGY8
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