MolNFT v1 · #387401 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (A1KGE7)
A1KGE7: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (A1KGE7)”. 17 pockets (best druggability 0.75). MolNFT v1 #387401 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A1KGE7
- Type
- protein
- Length
- 1,178 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4Ef77Afb5a3D9F41c95Be3227D1CC986CCb61835
- Molecule
- DNA-directed RNA polymerase subunit beta
- UniProt
- A1KGE7
- Pockets
- 17 · best druggability 0.75
Structure
1 distinct chain · 27% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit beta | protein | 1178 | 27% helix, 26% strand | A1KGE7 |
Pockets
17 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 698 | 0.75 | 0.81 | 73 | empty |
| 2 | 59 | 0.68 | 0.96 | 16 | empty |
| 3 | 400 | 0.67 | 0.80 | 55 | empty |
| 4 | 257 | 0.66 | 0.83 | 32 | empty |
| 5 | 467 | 0.60 | 0.75 | 44 | empty |
Compared structures
- 7KUG · Fe-S cluster-bound transcription activator WhiB7 in complex with the SigmaAr4-RNAP Beta… · an experimental structure of the same protein · chain A against D, TM-score 0.06
- 7KUG · Fe-S cluster-bound transcription activator WHIB7 in complex with the SIGMAAR4-rnap beta… · an experimental structure of the same protein · chain A against D, TM-score 0.06
- 7KUF · Transcription activation subcomplex with WhiB7 bound to SigmaAr4-RNAP Beta flap tip… · an experimental structure of the same protein · chain A against B, TM-score 0.05
- 7KUF · Transcription activation subcomplex with WHIB7 bound to SIGMAAR4-rnap beta flap tip… · an experimental structure of the same protein · chain A against B, TM-score 0.05
- 8CYF · WhiB3 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA · an experimental structure of the same protein · chain A against B, TM-score 0.05
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A1KGE7
- Elsewhere: UniProt A1KGE7 · AlphaFold DB A1KGE7
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