UniProt A1KGE7
RNA polymerase sigma factor, DNA-directed RNA polymerase subunit beta chimera (A1KGE7)
RNA polymerase sigma factor, DNA-directed RNA polymerase subunit beta chimera (UniProt A1KGE7), EC 2.7.7.6: 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 27 pockets. Binding sites, druggability and…
- UniProt
- A1KGE7
- Protein
- RNA polymerase sigma factor, DNA-directed RNA polymerase subunit beta chimera
- EC
- 2.7.7.6
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 27 · 6 records with a druggable one
Structures
6 records of A1KGE7 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7KUF | Transcription activation subcomplex with WhiB7 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA | x-ray diffraction | B | SF4 | 2 (best 0.67) |
| 7KUF | Transcription activation subcomplex with WHIB7 bound to SIGMAAR4-rnap beta flap tip chimera and DNA | x-ray diffraction | B | SF4 | 2 (best 0.67) |
| 7KUG | Fe-S cluster-bound transcription activator WhiB7 in complex with the SigmaAr4-RNAP Beta flap tip… | x-ray diffraction | B, D | SF4 | 2 (best 0.70) |
| 7KUG | Fe-S cluster-bound transcription activator WHIB7 in complex with the SIGMAAR4-rnap beta flap tip… | x-ray diffraction | B, D | SF4 | 2 (best 0.70) |
| 8CYF | WhiB3 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA | x-ray diffraction | B | SF4 | 2 (best 0.65) |
| A1KGE7 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (A1KGE7) | predicted | A | — | 17 (best 0.75) |
Ligands
- SF4 · Iron/sulfur cluster · in 5 records
Experiment against prediction
- 7KUG chain B against the predicted model A1KGE7: TM-score 0.47, RMSD 4.47 Å
- 7KUG chain B against the predicted model A1KGE7: TM-score 0.47, RMSD 4.47 Å
- 7KUF chain B against the predicted model A1KGE7: TM-score 0.47, RMSD 4.34 Å
- 7KUF chain B against the predicted model A1KGE7: TM-score 0.47, RMSD 4.34 Å
- 7KUG chain D against the predicted model A1KGE7: TM-score 0.47, RMSD 4.44 Å
- 7KUG chain D against the predicted model A1KGE7: TM-score 0.47, RMSD 4.44 Å
- 8CYF chain B against the predicted model A1KGE7: TM-score 0.46, RMSD 3.95 Å
Elsewhere
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