MolNFT v1 · #387226 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (A7ZUK1)
A7ZUK1: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (A7ZUK1)”. 19 pockets (best druggability 0.79). MolNFT v1 #387226 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A7ZUK1
- Type
- protein
- Length
- 1,342 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf47690e8C72689d1d40E0adD93091Ede78Dd4F1d
- Molecule
- DNA-directed RNA polymerase subunit beta
- UniProt
- A7ZUK1
- Pockets
- 19 · best druggability 0.79
Structure
1 distinct chain · 33% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit beta | protein | 1342 | 33% helix, 25% strand | A7ZUK1 |
Pockets
19 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 991 | 0.79 | 0.81 | 95 | empty |
| 2 | 504 | 0.74 | 0.83 | 50 | empty |
| 3 | 498 | 0.67 | 0.78 | 51 | empty |
| 4 | 56 | 0.66 | 0.95 | 15 | empty |
| 5 | 352 | 0.61 | 0.78 | 45 | empty |
Compared structures
- 4YLN · E. coli Transcription Initiation Complex - 17-bp spacer and 4-nt RNA · an experimental structure of the same protein · chain A against C, TM-score 0.99
- 4YLN · E. COLI transcription initiation complex - 17-bp spacer and 4-nt RNA · an experimental structure of the same protein · chain A against C, TM-score 0.99
- 4YLP · E. coli Transcription Initiation Complex - 16-bp spacer and 5-nt RNA · an experimental structure of the same protein · chain A against C, TM-score 0.99
- 4YLP · E. COLI transcription initiation complex - 16-bp spacer and 5-nt RNA · an experimental structure of the same protein · chain A against C, TM-score 0.99
- 4XSZ · Crystal structure of cbr 9393 bound to escherichia COLI RNA polymerase holoenzyme · an experimental structure of the same protein · chain A against C, TM-score 0.99
- 4XSZ · Crystal structure of CBR 9393 bound to Escherichia coli RNA polymerase holoenzyme · an experimental structure of the same protein · chain A against C, TM-score 0.99
- 4XSY · Crystal structure of CBR 9379 bound to Escherichia coli RNA polymerase holoenzyme · an experimental structure of the same protein · chain A against I, TM-score 0.98
- 4XSX · Crystal structure of CBR 703 bound to Escherichia coli RNA polymerase holoenzyme · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 4XSX · Crystal structure of cbr 703 bound to escherichia COLI RNA polymerase holoenzyme · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 4XSY · Crystal structure of cbr 9379 bound to escherichia COLI RNA polymerase holoenzyme · an experimental structure of the same protein · chain A against C, TM-score 0.98
- 4YLO · E. COLI transcription initiation complex - 16-bp spacer and 4-nt RNA · an experimental structure of the same protein · chain A against C, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7ZUK1
- Elsewhere: UniProt A7ZUK1 · AlphaFold DB A7ZUK1
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