MolNFT v1 · #386186 · protein

AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (Q7GED9)

Q7GED9: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (Q7GED9)”. 5 pockets (best druggability 0.58). MolNFT v1 #386186 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q7GED9
Type: protein
Length: 339 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x3fcD6ed69FF1FF21E33994A31d5818AC9e3aDb33
Molecule: DNA-directed RNA polymerase subunit alpha
UniProt: Q7GED9
Pockets: 5 · best druggability 0.58

Structure

1 distinct chain · 31% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA-directed RNA polymerase subunit alpha	protein	339	31% helix, 32% strand	Q7GED9

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	206	0.58	0.80	26	empty
2	136	0.53	0.80	18	empty
3	201	0.52	0.77	19	empty
4	116	0.37	0.74	19	empty
5	65	0.35	0.77	17	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7GED9
Elsewhere: UniProt Q7GED9 · AlphaFold DB Q7GED9

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