MolNFT v1 · #386062 · protein
AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit D (P39471)
P39471: “AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit D (P39471)”. 2 pockets (best druggability 0.31). MolNFT v1 #386062 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P39471
- Type
- protein
- Length
- 264 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x2BfFDbEAFa18c028B2FfB28D507b26e3fD3E6cf3
- Molecule
- DNA-directed RNA polymerase subunit D
- UniProt
- P39471
- Pockets
- 2 · best druggability 0.31
Structure
1 distinct chain · 28% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit D | protein | 264 | 28% helix, 38% strand | P39471 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 59 | 0.31 | 0.74 | 12 | empty |
| 2 | 50 | 0.30 | 0.76 | 15 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 7OK0 · Cryo-EM structure of the sulfolobus acidocaldarius RNA polymerase at 2.88 a · an experimental structure of the same protein · chain A against D, TM-score 0.95
- 7OK0 · Cryo-EM structure of the Sulfolobus acidocaldarius RNA polymerase at 2.88 A · an experimental structure of the same protein · chain A against D, TM-score 0.95
- 7OQY · Cryo-EM structure of the cellular negative regulator TFS4 bound to the archaeal RNA… · an experimental structure of the same protein · chain A against D, TM-score 0.94
- 7OQY · Cryo-EM structure of the cellular negative regulator TFS4 bound to the archaeal RNA… · an experimental structure of the same protein · chain A against D, TM-score 0.94
- 7OQ4 · Cryo-EM structure of the atv rnap inhibitory protein (rip) bound to the DNA-binding… · an experimental structure of the same protein · chain A against D, TM-score 0.94
- 7OQ4 · Cryo-EM structure of the ATV RNAP Inhibitory Protein (RIP) bound to the DNA-binding… · an experimental structure of the same protein · chain A against D, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P39471
- Elsewhere: UniProt P39471 · AlphaFold DB P39471
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